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  Vol. 138 No. 11, November 2002 TABLE OF CONTENTS
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  The Cutting Edge: Challenges in Medical and Surgical Therapeutics
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Topical Targretin and Intralesional Interferon Alfa for Cutaneous Lymphoma of the Scalp

Jennifer T. Trent, MD; Paolo Romanelli, MD; Francisco A. Kerdel, BSc,MBBS
From Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, Fla.

Arch Dermatol. 2002;138:1421-1423.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 56-year-old man presented with multiple red-violaceous firm, nontender nodules and plaques on the left frontal and parietal areas of his scalp (Figure 1). There was no regional lymphadenopathy. The patient denied any fever or chills. His medical history was significant for diabetes mellitus and hypertension, for which he was taking metformin, troglitazone, glyburide, and enalapril maleate. There was no personal or family history of cancer. A skin biopsy specimen from a scalp lesion showed a dense atypical lymphocytic infiltrate suggestive of malignant lymphoma (Figure 2). Results of extensive investigation including a bone marrow biopsy, lymph node biopsy, and computed tomographic scan of the chest, abdomen, and pelvis were negative for systemic lymphoma. A specimen from a repeated biopsy was submitted for flow cytometric analysis and Southern blotting for B- and T-cell receptor rearrangement. Immunophenotypic . . . [Full Text of this Article]

THERAPEUTIC CHALLENGE

SOLUTION

COMMENT



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