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Arch Dermatol. 2005;141:633-638.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Cutaneous leiomyoma associated with Reed syndrome.

MICROSCOPIC FINDINGS, LABORATORY FINDINGS, AND CLINICAL COURSE

The epidermis of the skin biopsy specimen was normal. A dense proliferation of spindle-shaped cells with eosinophilic cytoplasm and long nuclei was located in the dermis. These interweaving bundles of cells surrounded the vessels and the pilosebaceous apparatus. There was no cytologic atypia.

The complete blood cell count, serum chemistry profile, and serum erythropoietin levels were within normal limits, except for an increased level of -glutamyltransferase (121 U/L [reference range, 7-33 U/L]). Abdominal ultrasonography showed an angioma of the liver but no morphological abnormality of the kidneys or ovaries. Magnetic resonance imaging of the head showed no progression of the tumor. Nifedipine therapy (20 mg/d) was initiated, but the patient was unavailable for follow-up, and the efficacy of the treatment could not be evaluated.

DISCUSSION

Reed syndrome is an autosomal dominant condition with incomplete penetrance in which patients have cutaneous and uterine leiomyomas.¹ Tumors typically appear in early adult life. In . . . [Full Text of this Article]

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Arch Dermatol. 2005;141(5):633-638.
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