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Multiple Nodules in a Child—Quiz Case
Giuseppe Fabrizi, MD;
Calogero Pagliarello, MD;
Guido Massi, PhD
University of Molise, Campobasso, Italy (Dr Fabrizi); Oasi Institute for Research on Mental Retardation and Brain Aging (IRCCS), Troina, Italy (Dr Pagliarello); and Catholic University Medical School, Rome, Italy (Dr Massi)
Arch Dermatol. 2008;144(2):255-260.
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REPORT OF A CASE
A previously healthy 23-month-old white child presented with 7 firm, nonmobile, and nontender nodules located on the forehead, abdomen, hands, and knees (Figure 1). The lesions arose abruptly within 1 month, and the child's mother denied any trauma to the affected areas. The lesions had been treated by the primary care pediatrician with oral amoxicillin trihydrate, 1 g daily, without resolution. No superficial lymph nodes were palpable. The following laboratory test results were within reference range: complete blood cell count; blood chemistry studies; nuclear antibody; anti-Ro, anti-La, and anti-Sm antibodies; anti–double-stranded DNA antibodies; erythrocyte sedimentation rate; and serum amyloid A protein.
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A lesion of the knee was excised under local anesthesia and pathologically evaluated (Figure 2 and Figure 3).
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What is your diagnosis?
SECTION EDITOR: MICHAEL E. MING, MD, MSCE; ASSISTANT SECTION EDITORS: CARRIE ANN R. CUSACK, MD; SENAIT W. DYSON, MD; JACQUELINE M. JUNKINS-HOPKINS, MD; VINCENT LIU, MD; KARLA S. ROSENMAN, MD
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