This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Dermatology  • Dermatologic Disorders  • Acne  • Drug Therapy  • Drug Therapy, Other  • Alert me on articles by topic  Social Bookmarking   What's this?

YuJie Fu, PhD; LiYan Chen, PhD; YuanGang Zu, PhD; ZhiGuo Liu, PhD; Xia Liu, MS; Ying Liu, PhD; LiPing Yao, PhD; Thomas Efferth, PhD

Arch Dermatol. 2009;145(1):86-88.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Propionibacterium acnes is a gram-positive anaerobic microorganism recognized as the major skin bacterium causing acne.¹ Clove essential oil is the extract of Syzygium aromaticum (L) Merr et Perry. Its antimicrobial property has been reported,² but to our knowledge its antibacterial activity toward P acnes and the mechanism of action have not been reported.

Methods

Agar diffusion and broth microdilution methods were used to evaluate the activity of clove essential oil toward P acnes, and the mechanisms of action were investigated by flow cytometry (FCM), atomic force microscopy (AFM), and sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE).

Results
Clove essential oil exerted significant antibacterial activity toward P acnes (Table). The mean (SD) bacteriostatic diameter was 24.0 (0.5) mm. Both the minimum inhibitory concentration and minimum bactericidal concentration . . . [Full Text of this Article]

Comment

AUTHOR INFORMATION


CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?